A cultured autograft is a tissue grown from one’s own skin cells for use in placing on the person’s own body
What is a Cultured Autograft
A cultured autograft is a tissue grown from one’s own skin cells for use in placing on the person’s own body. The Cultured Epithelial Autograft procedure involves amplification of the patient’s keratinocytes in vitro using a simple biopsy, and then employing them as a permanent epidermis to replace the afflicted skin area. CEAs allow a significant surface expansion, which cannot be achieved with other surgical techniques based on autologous grafting. Despite this, CEAs have a low take rate in full-thickness beds (i.e., muscle fascia) and persistently infected locations. Furthermore, the CEAs preparations that are now available are difficult to use. A neodermis will ultimately grow in the absence of a dermal bed, but giving allograft skin or a more permanent allodermis may boost clinical acceptance by minimizing infection and providing a viable dermal substitute.
The Downsides of Cultured Autografts
Some drawbacks with the use of cultured autografts are:
- Surgical procedure costs
- Limited quantity
- Donor site hypersensitivity
Some risks included with having a cultured autograft are:
- Graft failure
- Blister formation
- Graft tearing
- Skin tightening
- Increased risk for skin cancer
Instructions for patients choosing Cultured Autografts
- Bathe with mild soaps and moisturize with mild lotions
- Use pressure garments
- Minimize sun exposure to affected areas
- Apply sunscreen to any open areas
- Avoid tanning beds/sun lamps
- Avoid harmful chemicals
If you have noticed any abnormal changes in your skin, immediately see your healthcare provider.
Join Our Vitiligo Community
Stay up-to-date on the latest news about treatments and managing symptoms. Sign up to get important email updates with relevant information.