Melanocyte-keratinocyte transplantation procedure (MKTP) is a surgical procedure for restoring skin pigmentation in individuals with all kinds of vitiligo and leukoderma who have failed to respond to pharmacological and/or phototherapy treatment.


What is MKTP?

Melanocyte-keratinocyte transplantation, or MKTP, is the name of the procedure. During surgery, melanocyte skin cells that give color to the skin, hair, and eyes are removed from healthy, pigmented parts of the body and transplanted to a pigment-less area. Pigmentation usually starts to return to the surgery area in about two months. To assess the efficacy and safety of MKTP, patients must have follow-ups within a 6-month and 12-month period. 

Are there risks involved with MKTP?

Yes, there are some risks involved with MKTP and they are:

  • Hypopigmentation
  • Hyperpigmentation
  • Infection
  • Increased or decrease in sensitivity at donor or recipient site
  • Poor repigmentation

Postoperative instructions for patients who choose MKTP

  • Limit movement of affected areas
  • Do not remove dressing for 4-7 days
    • Removal or displacement of dressing increases risk for infection
  • Pain medications like acetaminophen may be useful
  • Keep harmful chemicals away from area

Most surgery centers will give patients instructions on how to care for it further after dressing removal.

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