Split-Skin Grafting
A split-thickness skin graft involves your surgeon removing a thin layer of skin from one place of your body (donor site) and using it to cover a surgical wound (recipient site). If you’ve lost a lot of skin due to an infection, a burn, or surgery, you may need a split-thickness skin graft.


What is split-skin grafting
Split-thickness skin grafting is another tissue-grafting procedure used in the treatment of vitiligo that results in good, visually acceptable repigmentation at the recipient site while causing minimal scarring at the donor site.
Split thickness skin grafting (STSG) has risen to the top for better color and texture match, faster outcomes, and the best success rate. The epidermis and highest section of the superficial dermis are transferred to the underlying dermabraded vitiliginous area in order to transfer melanocytes and keratinocytes from the donor graft. Growth factors and cytokines generated during wound healing may aid in melanocyte migration, transplantation, and multiplication.
Because graft displacement is a concern on the neck and other mobile locations, longitudinal strips of grafts positioned parallel to the skin creases can be employed. Additionally, postoperative corticosteroids and topical psoralens with UVA were observed to improve pigmentation and minimize the time it took for the complete response to appear. The main disadvantage of this treatment is that taking a thin graft necessitates expertise. STSG, on the other hand, was proven to be a satisfactory method for lowering patient morbidity and enhancing the quality of life in our vitiligo patients in correctly selected patients with good operator experience, as evidenced by the enthusiastic patient reaction that we continue to receive.
Are the adverse effects of split-skin grafting?
Complications of split thickness skin grafting include:
- Hyperpigmentation
- Peripheral depigmentation
- Milia formation
- Graft rejection
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