Systemic Therapy
The aim of systemic treatments is to stop the progression of the disease (stabilization), so immune-modulating treatments should be considered at an early stage, particularly for vitiligo affecting the face.
What are Systemic Treatments?
Systemic treatments may be more effective than topical treatments. They also come with a higher risk of negative effects, and some of them can weaken one’s immunity. Despite the modest risk, these medicines may increase a person’s risk of infection or cancer in some situations.

What kinds of Systemic Treatments are used for treating Vitiligo?
Type of Therapy |
Efficacy of Treatment | Notes |
Oral Steroids |
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Methotrexate |
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Ciclosporin |
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Mycophenolate Mofetil |
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Tetracycline |
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Subcutaneous Afamelanotide |
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Depigmentation Therapy |
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Cryotherapy |
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